Biologics

The NIBR Biologics Center (NBC) focuses on the discovery of biologics, primarily antibodies and protein drugs, and more recently, on the discovery of siRNA-based therapeutics. As a class of medicine, biologics are a powerful tool that can often treat diseases that cannot be treated with traditional approaches.

Antibody and proteins drugs are produced using recombinant DNA technology. Therapeutic antibodies are similar to those made by the human immune system, but are designed in the laboratory to specifically bind to disease targets in the body.

Therapeutic proteins are often identical or similar to naturally occurring proteins in the body, but they are used to replace, augment, or inhibit some function related to diseases.

RNAi therapeutics offer a new (modal) opportunity to treat disease and potentially can target any protein (gene) in a cell.

NBC concentrates on the discovery of antibodies, recombinant proteins and siRNA-based therapeutics.

 

 

Selected publications

• Geisse S. Reflections on more than 10 years of TGE approaches. Protein Expr Purif. 2008 Nov 7.