Modeling our microbial selves: insights from the zebrafish intestine
14 December 2016 12:00 to 13:00 EST
220 Mass. Avenue, Cambridge MA - USA
Speaker: Karen Guillemin, PhD Alec and Kay Keith Professor Department of Biology and Institute of Molecular Biology University of Oregon
Seminar Abstract: Microbial colonization of the digestive tract is a crucial event in vertebrate development. Our group has developed gnotobiotic zebrafish as a model system to study how intestinal microbial communities are established, how they influence host development, and how perturbations of the microbiota can result in loss of intestinal homeostasis and inflammation. New research from our group has demonstrated the importance of gut microbiota members in development of the pancreas and specifically the insulin-producing beta cell population.
Entry instructions: There is no cost to attend the seminar. If you are interested in attending please contact Meghan Spencer. Please check in with security at the Novartis visitor's entrance of 220 Massachusetts Avenue and you will be directed to the location of the seminar.
Speaker | Karen Guillemin, PhD
Karen Guillemin is the Alec and Kay Keith Professor in the Department of Biology and the Institute of Molecular Biology at the University of Oregon. She is also the founding director of the Microbial Ecology and Theory of Animals (META) Center for Systems Biology, an NIH funded National Center for Systems Biology. Guillemin received her bachelor’s degree in Biochemical Sciences from Harvard College and her Ph.D. from the Department of Biochemistry at Stanford University School of Medicine, where she worked with Dr. Mark Krasnow studying organ development in the model organism of the fruit fly. She continued her postdoctoral training at Stanford in the Department of Microbiology and Immunology, studying bacterial-host interactions with Dr. Stanley Falkow, studying the bacterial pathogen and carcinogen, Helicobacter pylori. As a faculty member at the University of Oregon, she established a research program that combines her interests in animal development and bacterial-host interactions. Her research group has been instrumental in pioneering the use of gnotobiotic zebrafish to study how resident microbial communities assemble and modulate host biology.